Syed Babar Ali School of
Science and Engineering
Syed Babar Ali School of Science and Engineering
Syed Babar Ali School of Science and Engineering (SBASSE) at LUMS is the first private research school of science and engineering in Pakistan. In higher education, the term research school refers to a model of teaching and scholarship practised by some of the best institutions in the world where the primary function of the university is to create and disseminate new knowledge. SBASSE has consciously modelled itself along the lines of the world’s top research schools and has a highly qualified faculty to accomplish its mission. The hallmark of SBASSE is its no-boundaries philosophy, which encourages cross-disciplinary collaborations not only between various disciplines at SBASSE but also those offered by other Schools at LUMS.
A Different Kind of
Science and Engineering School
in Pakistan
300,000
Square feet of lab and
classroom learning space
70+
Dedicated labs for research,
teaching and support
Accredited by
PEC and NCEAC
Choose your path
Science for Pakistan
Contribution in Science and Technology by the researchers at SBASSE has an impact on the future development of Science in Pakistan.
Meet our Faculty
At SBASSE our faculty members share the boundaries of their life experiences and interests that foster a dynamic learning environment on campus.
Research and Impact
Sulfonamides are vital components in many…
Sulfonamides are vital components in many pharmaceuticals and agrochemicals, yet traditional synthesis methods face challenges due to instability and harsh reaction conditions. In response, Dr. Ghayoor Abbas Chotana from Department of Chemistry and Chemical Engineering SBASSE along with his team members Ismat Nawaz, Maryam Nawaz, and Dr. Rahman Shah Zaib Saleem, have developed an innovative catalytic approach for Sulfur (VI) Fluoride Exchange (SuFEx) reactions, published in Advanced Synthesis & Catalysis.
Using affordable organic bases and leveraging the unexpected role of glass reaction vessels, the team’s method simplifies sulfonamide synthesis while adhering to green chemistry principles. This breakthrough enables safer, more efficient production of sulfonamides for drug discovery and highlights how everyday materials like glass can influence chemical reactions.
Read Full Paper here.
The work reflects LUMS’ commitment to advancing science and sustainability, contributing to global innovation in chemistry.
Dr. Basit Yameen, from the Department of…
Dr. Basit Yameen, from the Department of Chemistry, has made remarkable contributions to the field of polymer chemistry over the years. In 2014-15, he was recognized as an Emerging Investigator by the Royal Society of Chemistry’s Polymer Chemistry journal. Now, nearly a decade later, he has been honored once again, this time being identified and recommended by the journal’s editorial and advisory boards as one of the Pioneering Investigators who have firmly established themselves as pioneers of the field of polymer chemistry. This prestigious recognition celebrates Dr. Yameen’s lasting and impactful contributions to the advancement of polymer science, further solidifying his position as a leading figure in the field.
Dr. Nauman Zaffar Butt in the Electrical Engineering department leads…
Dr. Nauman Zaffar Butt in the Electrical Engineering department leads our efforts on photovoltaics which has now crossed over into the realm of agriculture, to produce the budding field of agrivoltaics. Powering agricultural farms through solar energy requires creative designs in both the solar cells as well as how solar cells will be integrated into a solar system that can power agri-farms.
Dr. Butt's PhD student Hassan Imran has now produced an amazing body of work that helps achieve both of these tasks. Novel materials, novel designs of the heterofacial structure of solar cells and employing two-dimensional layers of graphene or carbon nano-tubes can boost the performance of solar cells, achieving almost thermodynamically maximum efficiencies. Creative ways to interface silicon based and organic-inorganic solar cell technologies helps achieve the best of both worlds.
Finally, Hassan has mathematically modeled the role of soil and orientation of solar panels, in achieving high efficiency crop yield from solar enhanced farmlands. This work has immense implications for the country which calls for innovative solutions to address critical problems at the food-energy-water confluence.
The quality of his work is evidenced by the four articles published in the world's leading journal on this topic:
- The IEEE Transactions on Electron Devices [here, here, here and here],
- The IEEE Journal of Photovoltaics [here],
- Solar Energy [here] and
- Renewable Energy [here],
- along with several conference proceedings.
The Water-Food-Energy nexus remains one of the six forefront areas being pursued at the Syed Babar Ali School of Science and Engineering.
In the hustle and bustle of Pakistan's…
In the hustle and bustle of Pakistan's healthcare landscape, a silent war is raging, and it's not against a visible foe but rather microscopic troublemakers – antibiotic-resistant microbes.
Antibiotic resistance poses a growing threat to health globally. According to a report by Fleming on Antimicrobial Consumption by 700,000 individuals each year lose their lives to resistant infections. In Pakistan, this issue is exacerbated by a lack of antimicrobial stewardship in hospitals, indiscriminate antibiotic prescriptions, and a surge in respiratory diseases due to polluted air.
Healthcare providers, lacking the much-needed antimicrobial stewardship, are caught in a loop of overreliance on intravenous and oral antimicrobials. It's a revelation that makes you wonder – are we unintentionally brewing a storm of resistance right under our noses?
There's a surprising twist in the narrative of antimicrobial resistance. The air we breathe carries pollutants and potentially acts as a highway for antibiotic-resistant genes. A study by Lancet, a reputed medical journal, reveals a compelling connection between PM 2.5 air pollution and antibiotic resistance. PM 2.5 refers to particulate matter with a diameter of 2.5 micrometers or smaller. As these particles carry bacterial genomic material, inhaling them contributes to incorporating resistant genes into opportunistic pathogens, exacerbating antibiotic resistance.
Analyzing global data from 116 countries between 2000 and 2018, the study estimated that a 10% rise in annual PM 2.5 led to a 1.1% increase in aggregate antibiotic resistance, resulting in approximately 43,654 premature deaths. Regional variations highlighted potential significant increases in antibiotic resistance in Africa and Asia. Notably, for Pakistan, a 10% PM 2.5 elevation was predicted to increase antibiotic resistance by 2.6%.
To tackle this, Dr. Shaper Mirza has been at the forefront of addressing antibiotic resistance in Pakistan. She is actively engaged in projects addressing different facets of antibiotic resistance and stewardship. She participated in development of the first National Action Plan for Antimicrobial Resistance in Pakistan. The initiative involves identifying rates of antimicrobial resistance from a One-Health perspective in Pakistan. This was the first effort of its kind which furnished sufficient data suggesting resistance across all sectors which include human health, animal health and agriculture. The investigation and its outcome led to the development of National Action Plan for AMR in Pakistan. The National Action Plan was implemented in Pakistan in 2017 and currently there are 43 sentinel sites collecting and reporting data on antimicrobial resistance strains. The Situation analysis for National Action Plan was done in collaboration with Global Alliance for Antimicrobial Resistance Partnerships (GARP). The GARP consortium, comprising seven countries, collaborates to exchange knowledge, build capacity, and develop antimicrobial stewardship guidelines.
To improve on stewardship practices, Dr Mirza in collaboration with Pakistan Kidney and Liver Institute (PKLI) developed two courses on adult and pediatric antimicrobial stewardship. Both courses were very well attended both by physicians and basic science researchers working in the field of antimicrobial resistance.
Tips from the experts:
As Pakistan grapples with the dual challenges of smog and antibiotic resistance, practical steps can make a difference. When the air is thick with smog, consider preventive measures like wearing masks, frequent nasal cleaning to minimize pollutant exposure and emphasizing a high-protein diet to bolster immune systems.
While smog-induced respiratory symptoms might initially prompt concern, antibiotics are specifically designed to combat bacterial infections, not viral foes. Viruses, often the culprits behind seasonal respiratory ailments, don't respond to antibiotics. Therefore, before rushing to antibiotics, look for telltale signs of a bacterial infection – persistent high fever, green or discolored mucus, and specific radiological findings in chest X-rays. If symptoms persist, consult a healthcare professional who can guide you on the most effective and responsible course of action. By adopting these practices and following World Health Organization’s (WHO) guidelines for antibiotic usage, we protect ourselves from the smog's impact and contribute to the collective effort to preserve the effectiveness of antibiotics for when they're truly needed.
After all, a breath of fresh air should be just that – fresh and invigorating!
Selenium is a vital trace element that plays…
Selenium is a vital trace element that plays a crucial role in our health, influencing various biochemical pathways due to its antioxidant properties. In nature, it often finds its way to our plates through foods like tuna, enriching our bodies with its antioxidant prowess.
The intricate relationship between Selenium and antioxidant properties has been extensively studied by researchers in the field, including Dr. Rahman Shah Zaib Saleem from the Department of Chemistry and Chemical Engineering at SBASSE, who is one of the contributors to a paper on Selenium derivatives. The paper was published after Dr. Rahman’s DAAD (Deutscher Akademischer Austauschdienst) scholarship visit to Germany in 2019 in collaboration with eleven international researchers, including Dr Rama Alhasan, Dr. Guilherme M. Martins, Dr. Pedro P. de Castro, Dr. Claus Jacob.
Selenium, acting as an antioxidant powerhouse, takes center stage in this study. Nature carries very few selenium containing organic compounds, Selenoneine being one of those. In this work, the team has worked on the preparation of novel organoselenium compounds. The research zeroes in on Selenohydantoin derivatives, synthetic compounds inspired by Selenoneine. These derivatives, with their fascinating range of pharmacological applications, hold the potential to serve not just as antioxidants but as versatile agents with capabilities spanning anti-inflammatory, anticancer, and antiplatelet realms. Through Selenocysteine enzymes like Glutathione Peroxidase, it acts as a powerful defender, effectively reducing peroxides to explore their potential in combating oxidative stress, a state where an imbalance occurs between the production of free radicals and the body's ability to neutralize them.
Using a unique synthetic method, the researchers synthesized Selenohydantoin molecules, paving the way for a comprehensive evaluation of their antioxidant capabilities. The study employed classical radical scavenging and metal-reducing techniques to unravel the true potential of these synthetic compounds. Cytocompatibility assays demonstrated that the Selenohydantoin derivatives were not only effective antioxidants but also non-toxic to primary human aortic smooth muscle cells. Cytocompatibility refers to the compatibility of a substance with living cells, ensuring that these compounds do not harm or disrupt normal cell function, a promising aspect for further biological evaluations.
Among the synthesized compounds, those adorned with trifluoro-methyl (-CF3) and chlorine (-Cl) substituents emerged as molecules displaying noteworthy antioxidant activities. Dr. Rahman's work highlights these compounds as potential candidates for future biological studies, offering hope for innovative therapies against chronic diseases. This research focuses not only on synthetic compounds but also on the broader context of organoselenium compounds in living organisms. Looking into the future a larger picture emerges - synthesis of Selenium-based compounds could play a crucial role in developing novel and effective prevention and treatments for diseases such as cancer, cardiovascular diseases, cystic fibrosis and rheumatoid arthritis.
Dr. Rahman has recently been honored with another DAAD (Deutscher Akademischer Austauschdienst) scholarship grant by the German Academic Exchange Service. Through the scholarship Dr. Rahman and his research team will delve into the study of various signaling proteins and kinases, with a particular focus on the innovative molecule known as Proteolysis Targeting Chimeras (PROTACs). To learn more about Dr. Saleem's cutting-edge research and the potential impact of PROTACs on cancer treatment, follow this link.
Graduate Theses
The Particle
The Particle
A Science magazine with research and science stories from SBASSE.
Please click here to read the magazine: Issue 22
Science Stories
We are delighted to share that Dr. Khurram Bashir, Associate Professor in the Syed Babar Ali School of Science and Engineering (SBASSE), has been granted tenure.
Dr. Bashir earned his PhD in Agricultural Biotechnology from the University of Tokyo. Following his doctoral studies, he worked as a researcher at RIKEN, a leading scientific research institute in Japan. In 2021, he joined LUMS as an Associate Professor.
Dr. Bashir’s research focuses on understanding how plants respond to various abiotic stresses, including mineral deficiencies, drought, and heat stress. His work involves identifying the molecular functions of specific genes using advanced biotechnological tools and developing transgenic crops that demonstrate improved tolerance to these stresses.
In 2024, Dr. Bashir received the prestigious RIKEN EIHO (Significant Achievement) Award for his groundbreaking research on enhancing plant abiotic stress tolerance through the use of ethanol.
Please join us in congratulating Dr. Khurram Bashir on this significant milestone and wishing him continued success in his research and academic endeavors at LUMS!
We are delighted to share that Dr. Khurram Bashir, Associate Professor in the Syed Babar Ali School of Science and Engineering (SBASSE), has been granted tenure.
…Seminars and Conferences
Rizwan Ur Rehman Sagar completed his PhD (2010–2015) degree in Materials Science and Engineering, Tsinghua University, Beijing, China. He has been served as post-doctorate fellow (2016-2018) in College of Materials Science and Engineering, Shenzhen University. During that period, he was awarded research funding from Postdoctoral Science Foundation of China. In addition, he has been selected as an excellent postdoc (2018-2020) from Tsinghua Shenzhen International Graduate School, Shenzhen, China and and obtain a prestigious research funding from the National Natural Science Foundation as PI. He also served Jiangxi University of Science and Technology, Ganzhou, as Associate Professor where he got another prestigious award of Foreign Research Expert in China-2022. He is actively engaged in the fabrication of low-dimensional materials high energy density battery research. He has been published more than 80 scientific articles in well-reputed journals and also served Associate Editor in different journals especially Nanoscience-Frontiers in Chemistry. Recently, he is working in the Institute for Frontier Materials, Deakin University-Geelong Australia.
Rizwan Ur Rehman Sagar completed his PhD (2010–2015) degree in Materials Science and Engineering, Tsinghua University, Beijing, China. He has been served as post-doctorate fellow (2016-2018) in College of Materials…
This masterclass is intended for advanced training in quantum algorithms for students, researchers, and faculty members. The masterclass will assume foundational knowledge of quantum computing and basic algorithms. The selection will be based on prior experience in quantum computing and is independent of the academic level of the applicants. Those applicants will be selected who have sufficient training in basic quantum computing to understand the lectures. The masterclass will be held in-person, but the recordings will be made available at the QuantuC channel.
This upcoming Master Class on Quantum Algorithms is happening on
Date: November 22nd - 24th, 2024
Time: From 8 AM to 5 PM
Venue: Room 10-201, 2nd Floor SBASSE Building LUMS
Application Deadline: November 7th, 2024
Master Class will cover the following topics
Interactive Proofs with Quantum Devices
Quantum Algorithms for Welded Trees
Constrained Optimization Algorithms
Variational Quantum Algorithms
Distributed Quantum Computing Algorithms
Hamiltonian and Open Quantum System Simulation
Noise Mitigation Algorithms for Quantum Sensing
Quantum Key Distribution Algorithms
Quantum Communication Complexity
Lecturers:
Jibran Rashid, IBA Karachi
Bilal Tariq, NCP Islamabad
Muhammad Faryad, Ayesha Khalique, Adam Zaman, SBASSE, LUMS Lahore
Please note that the participants will be provided refreshments and daily lunch, but they are expected to arrange their own travel and accommodation. Limited funds are available for accommodation for students who cannot arrange it and demonstrate the need. Selected participants will be informed via email within one week of the deadline.
Organizers: SPIE Chapter at LUMS and SBASSE
If you have any questions, feel free to contact us:
For Technical Queries: muhammad.faryad@lums.edu.pk
For Logistics Queries: arshad.maral@lums.edu.pk
This masterclass is intended for advanced training in quantum algorithms for students, researchers, and faculty members. The masterclass will assume foundational knowledge of quantum computing and basic algorithms. The…
Public Lecture Series
Biography:
Dr. Sarah Qureshi is working on contrail-free aero engines as the CEO and founding director of Aero Engine Craft (Pvt) Ltd. She is also a visiting fellow at the School of Aerospace at Cranfield University. Sarah has a PhD degree in Aerospace Engineering from Cranfield University, UK. Her area of specialization is Propulsion whereby she worked on the development of a contrail-free aero-engine that has been derived from a novel patented technology. Sarah was actively involved with the invented technical outcome of the engine. The innovated engine has a tremendous potential in bringing about an environmental revolution in the context of aviation.
Dr. Sarah Qureshi , along with the inventor of technology Mr. Masood Latif Qureshi has now set up Aero Engine Craft (Private) Limited as Pakistan's first commercial engine and aircraft company to convert this patented technology into a full scale commercial application ready to be used by modern civil transport aircraft. During her PhD, Sarah supervised a number of MSc. students for their research projects on Jet Engine Technology. Prior to this, Sarah completed her master’s degree in the field of Aerospace Dynamics from Cranfield University, UK. Her research involved the design of a trajectory following controller inclusive of stability augmentation, attitude control system and outer loop autopilot for unmanned aircraft (UAVs) flying in close formation for the purpose of air to air refuelling. After graduating as a Mechanical Engineer from Pakistan, Sarah gained extensive experience of working in the local automotive and engineering industry.
Her bachelors' research project involved the development of a measurement and data logging system for the in-cylinder temperature and combustion of an internal combustion engine. Her prime technical interests are focused upon engine technology and aircraft design. Sarah holds a Private Pilot License (PPL) with 70 hours of Flying Experience. She has also learned acrobatic flying and several flight manoeuvres while at Cranfield.
Biography:
Dr. Sarah Qureshi is working on contrail-free aero engines as the CEO and founding director of Aero Engine Craft (Pvt) Ltd. She is also a visiting fellow at the School of Aerospace at Cranfield University. Sarah has a PhD degree in Aerospace Engineering from…
سائنس اور ٹیکنالوجی کی کہانیاں
علم و تحقیق کی دنیا میں، کچھ افراد اپنی شاندار کامیابیوں کی وجہ سے ہی نہیں بلکہ ان کے حصول کی تگ و دو میں درپیش سفر کی وجہ سے بھی نمایاں ہوتے ہیں۔ ڈاکٹر عفان رزاق، لاہور یونیورسٹی آف مینجمنٹ سائنسز (لمز )کے ایک شاندار سابقہ طالب علم ہیں، جن کی کہانی شوق، ثابت قدمی، اور اختراع کے جذبے کا عملی مظاہرہ کرتی ہے۔ اپنی نہایت سادہ شروعات سے لے کر فیڈرل ڈرگ ایجنسی (ایف ڈی اے) میں ملازمت تک ، ڈاکٹر عفان کا سفر قابل رشک اور تقلید ہے۔
ڈاکٹر عفان کا تعلیمی سفر لمز سے شروع ہوا، جہاں انہوں نے سید بابر علی اسکول آف سائنس اینڈ انجینئرنگ (ایس ایس ای) سے برقی انجینئرنگ میں ماسٹرز ڈگری حاصل کی۔یہیں ڈاکٹر عفان نے کنٹرول سسٹمز اور خاص طور پر بین المضامینی اطلاقات میں اپنی دلچسپی کو دریافت کیا۔ خاص طور پر لمز میں ان کی ہائیڈرولوجیکل سسٹمز پر مبنی تحقیق نے ان کے مستقبل کے ارادوں کی بنیاد رکھی ۔
لمز میں بیتائے گئے اپنے وقت کا ذکر کرتے ہوئے، ڈاکٹر عفان اس تبدیلی کے تجربے کو بڑے شوق سے یاد کرتے ہیں جس نے روایتی حدود سے ہٹ کر کنٹرول سسٹمز کے ممکنہ استعمال پر ان کے نقطہ نظر کو وسیع کیا۔ جرمنی کی یونیورسٹی، ٹی یو کائزرلاوٹرن، میں ایک مختصر مدت سمیت جدید تحقیق اور بحرانی تعاون کے منصوبوں نے ان کے تجسس کو بڑھایا اور انہیں علمی فضیلت کی راہ پر گامزن کیا۔
معاشرتی مسائل کو اپنے علم سے حل کرنے کے جذبے سےسرشار، ڈاکٹر عفان نے امریکن یونیورسٹی آف لوئی ویل ، امریکہ، میں علمی سفر شروع کیا۔ ڈاکٹر تامر انانک کی رہنمائی میں ان کا تحقیقی کام گردے کی دائمی بیماری کی خصوصیات اور دواؤں کی خوراک کی تشکیل پر مبنی تھا، جس نے ان کے مستقبل کے کام کو شکل دینے میں مدد کی۔
ان کے راستے میں کئی رکاوٹیں آئیں، جیسے کہ کووڈ-١٩ کے وبائی زمانے میں آن لائن تعلیم کے نظام اور مریض کے ڈیٹا کی کمی، لیکن اس کے باوجود ڈاکٹر عفان کی محنت اور استقامت برقرار رہی۔ مریضوں کے ورچوئل ماڈلز اور جدید تحقیقاتی طریقوں کا فائدہ اٹھاتے ہوئے، انہوں نے اپنی تحقیق میں نمایاں پیش رفت کی، جس کے نتیجے میں انہیں اشاعت کا ایک شاندار ریکارڈ اور اپنی اہم شراکت کے لیے باوقار ایوارڈ حاصل ہوئے۔
ڈاکٹر عفان کے موثر ترین تحقیقاتی منصوبوں میں سے ایک دواؤں کی انفرادی خوراک کے لیے ایک ماڈلنگ اور کنٹرول فریم ورک تیار کرنے پر مرکوز ہے، جو خاص طور پر گردے کی دائمی بیماری اور وارفارن کے انتظام سے منسلک ہے۔ ان کا کام نہ صرف ذاتی ڈوزنگ پمپس کے ذریعے صحت کی دیکھ بھال کی فراہمی میں انقلاب لانے کی حامی بھرتا ہے بلکہ انسانی زندگی کے معیار کو بڑھانے میں کنٹرول سسٹم کی صلاحیت کو بھی اجاگر کرتا ہے۔
اپنے تعلیمی سفر کی زینت بننے والی تعریفوں اور اعزازات کے ساتھ، ڈاکٹر عفان کی نئی ایف ڈی اے میں پوسٹ-ڈاکٹریٹ کی پوزیشن قبول کر کے ایک نیا موڑ لیا۔ دواؤں کے ردعمل کو سمجھنے کے لیے ریاضیاتی ماڈل تیار کرنے کی ان کی اولین ترجیح، ان کی سابقہ تحقیق سے نہ صرف ہم آہنگ بلکہ اصولی فیصلوں اور دواؤں کی منظوری کے عمل پر وسیع اثرات کی حامل بھی ہے۔
ڈاکٹر عفان اپنے سفر کو مد نظر رکھتے ہوئے، محققین اور انجینئرز کو ایک قیمتی مشورہ دیتے ہیں: اچھے استاد ڈھونڈیں، تجسس کو قبول کریں، اور سمجھ کے مشکلات کا حل نکالیں۔ ان کا منتر ”اچھا کریں، چاہے اثر ہو یا نہ ہو“ ان کی مہارت کو انسانیت کی بہتری کے لیے استعمال کرنے کا اظہار کرتا ہے۔
لمز کی تاریخ میں، ڈاکٹر عفان ایک روشن مثال ہیں، جو تعلیم، رہنمائی، اور کامیابی کی ایک عمدہ مثال ہیں۔ ایس ایس ای کے کمرہ جماعت سے لے کر ایف ڈی اے تک، ڈاکٹر عفان کا سفر ان لوگوں کی بے پناہ صلاحیتوں کی عکاسی کرتا ہے جو خواب دیکھنے کی ہمت کرتے ہیں اور دنیا کو بہتر بنانے کی کوشش میں مگن رہتے ہیں۔
علم و تحقیق کی دنیا میں، کچھ افراد اپنی شاندار کامیابیوں کی وجہ سے ہی نہیں بلکہ ان کے حصول کی تگ و دو میں درپیش سفر کی وجہ سے بھی نمایاں ہوتے ہیں۔ ڈاکٹر عفان رزاق، لاہور…