Future factories are believed to be intelligent, reconfigurable, and adaptable to market dynamics. The vision of batch-size-one production and mass-personalization is not so far from becoming a reality. Technologies are getting available and are becoming 'smart' with each passing day. Ever-increasing computing power, big data, and smart robots are forming this new wave of smart manufacturing. Contrary to conventional automation, teams of humans and robots can expand the level of automation in areas that have conventionally been difficult to automate. Digital twin as a data connected virtual copy of a physical system can address the complexity of such human-robot teaming. Humans as future operators are desired to interact with machines through immersive technologies. Such a future manufacturing ecosystem is referred to as Industry 4.0. Besides discussing the manufacturing 4.0 strategies by different companies, the lecture will present an outlook on emerging manufacturing technologies, and their practical use cases.