Functional organisation of the genome in 3D
Dr. Stefan Schoenfelder is a young group leader at Babraham Institute in Cambridge, UK and he has contributed enormously in the field of three dimensional chromosomal organization in nucleus and how it is linked to gene expression patterns during development.
Dr. Stefan Schoenfelder studied molecular biology at the University of Heidelberg, Germany. He received his PhD in 2005 from Centre for Molecular Biology in Heidelberg, studying the mechanism of a transcriptional silencer in the mouse H19/Igf2 imprinting control region. In 2005, he joined the lab of Peter Fraser at the Babraham Institute in Cambridge (UK), where he first focused on the spatial organisation of transcription in mouse erythroid cells. He established a novel method to map long-range enhancer-promoter interactions genome-wide at high resolution. Since 2018, Dr. Schoenfelder is a group leader at the Babraham Institute. His current research focus is to decipher how cis-regulatory variation underpins the functional heterogeneity between human induced pluripotent stem cells.